Special Issue "Genetics and Genomics of Blood Disorders"

Blood disorders comprise a large number of oncologic and non-oncologic diseases affecting all hematologic cell lineages. Some genetic alterations have been known as the cause of these diseases for many decades. Conversely, other specific genetic features have been linked to these diseases only recently.

Technological advances have had a huge impact on the discovery of new genomic features and are useful in defining the sequential acquisition of genetic alteration during disease evolution. Furthermore, the effort to correlate genetic abnormalities and patients’ outcomes is helping us to understand the impact of such alterations on disease evolution.

As a result, a new special issue in Genes on “Genetics and Genomics of Blood Disorders” will provide an overview of the known genetic features of different hematologic diseases and recent observation in this expanding field.